| Binary fission | Multiple fission |
| 1. Splitting of unicellular organisms like amoeba into two equal halves during cell division is termed binary fission. | 1. Division of single-celled organisms such as malarial parasites into many daughter cells simultaneously is termed multiple fission. |
| 2. Amoeba and Bacteriadivide by binary fission. | 2. Plasmodium divide by multiple fission |
